Jobs at Axle Informatics

Implements and monitors cybersecurity controls across Linux, Kubernetes, database, and model-serving environments. Builds monitoring, detection, vulnerability scanning, hardening automation, secrets management, network policy, access control, and evidence collection. Supports AI security tooling, documentation, testing, security reviews, continuous monitoring reports, and federal authorization activities. This early-career role includes hands-on training, certification support, and collaboration with AI and systems administration leads.

Build production AI retrieval and knowledge systems for rare disease research at NIH. Model biomedical ontologies in PostgreSQL, develop semantic search, retrieval-augmented services, ranking, evaluation, and observability, and deliver user interfaces with Next.js, React, and TypeScript. Deploy and operate services in on-premises and HPC Kubernetes environments, including GPU inference. Collaborate with NIH staff, clinicians, and researchers, and contribute to scientific publications.

Build and operate agentic AI systems for rare disease research, including multi-turn workflows, structured and validated outputs, tool calling, prompt testing, evaluation suites, asynchronous execution, streaming, observability, and failure handling. Collaborate with NIH staff, clinicians, geneticists, researchers, and patient communities to translate needs into reliable data models and system behavior. Own components through deployment, establish AI engineering standards, and contribute to scientific manuscripts, abstracts, and conference posters.

Leads multidisciplinary teams across data engineering, AI/ML, scientific computing, and modeling to build reliable biomedical research systems. Sets technical strategy, guides production data platforms, advances responsible AI, and establishes standards for reproducibility, governance, security, observability, and delivery. The role moves research prototypes into dependable production capabilities, develops technical leaders, supports federal proposals, and partners with scientists, engineers, security teams, and government stakeholders.

Provides scientific and medical consultation for CDC public health research and surveillance projects. Designs and evaluates studies, reviews protocols and proposals, supports standardized project procedures, writes manuscripts and reports, presents findings, communicates with public health stakeholders, and helps develop contracts and policy documents while ensuring compliance with applicable requirements.

Build scalable full-stack applications using TypeScript, Node.js, and Angular; design and implement RESTful services; create responsive web interfaces; and write unit and end-to-end tests. Collaborate in an Agile team on prototyping, testing, code reviews, and cloud-native applications using containers and orchestration tools.

Develop and maintain reproducible bioinformatics pipelines and multi-omics data products. Perform statistical modeling, ML, and integration of genomic, transcriptomic, spatial, proteomic, and clinical datasets. Build researcher-facing dashboards, notebooks, and APIs; ensure FAIR, containerized, version-controlled analyses; collaborate with scientists, engineers, and government stakeholders to enable reusable, secure, analysis-ready data workflows.