Post Doctoral Scientist- Human Genomics and Translational Data Science

About us:

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About our client:

Global healthcare leader headquartered in Indianapolis, Indiana. The Cardiometabolic Research (CMR) Therapeutic Area of our client, focuses on the discovery of biologic, small molecule and genetic therapeutics for the treatment of cardiometabolic diseases and associated complications. 

We are seeking a Statistical Geneticist with expertise in whole genome sequencing (WGS), proteomics, and clinical outcomes analysis to advance our research in identifying novel therapeutic targets. This role will involve analyzing large-scale biobank and population-cohort datasets to uncover genetic and molecular factors associated with disease risk, progression, and treatment response. You will operate as part of the CMR Data Science and Computational Biology (DSCB) team and partner with early discovery scientists and clinicians, translational scientists, bioinformaticians and geneticists.

Key Responsibilities

• Apply statistical and computational approaches to analyze WGS/WES, proteomics, metabolomics, and clinical data for biomarker discovery.
• Conduct rigorous analyses of large-scale population cohorts and biobank datasets to identify genetic variants and causal genes associated with disease outcomes.
• Develop and implement machine learning and bioinformatics pipelines to integrate multi-omics data.
• Collaborate with interdisciplinary teams, including geneticists, epidemiologists, and clinicians, to interpret findings and guide therapeutic development.
• Prepare scientific reports, presentations, and publications detailing research outcomes.
• Contribute to the development of novel statistical methods for analyzing high-dimensional biological data.

Qualifications & Requirements

• PhD in statistical genetics, bioinformatics, computational biology, biostatistics, or a related quantitative field
• Qualified applicants must be authorized to work in the United States on a full-time basis.

Additional Skills/Preferences

• Expertise in whole genome and whole exome sequencing analysis, proteomics, metabolomics and other molecular data analysis, and clinical outcomes research.
• Strong proficiency in statistical modeling, machine learning, and high-dimensional data analysis.
• Experience working with large biobank and cohort datasets (e.g., UK Biobank, All of Us, FinnGen).
• Proficiency in programming languages such as R, Python, and SQL for data analysis.
• Familiarity with genetic association studies, GWAS, and polygenic risk scores.
• Excellent communication and collaboration skills to work effectively in cross-functional teams.
• Experience in pharmaceutical or biotech industry settings.
• Knowledge of functional genomics and multi-omics data integration.
• Strong publication record demonstrating contributions to statistical genetics and biomarker discovery and analysis.
• Prior experience in cardiometabolic research.
• Prior experience with polygenic risk score models.

This is an exciting opportunity to advance precision medicine and therapeutic target identification through innovative statistical genetics approaches. If you are passionate about employing big data for scientific discovery, we encourage you to apply!

• Attractive, market-leading salary package.
• Clear career advancement path with professional development opportunities.