Genentech Logo

Genentech

Principal Software Engineer

Sorry, this job was removed at 04:32 p.m. (EST) on Thursday, May 01, 2025
Be an Early Applicant
In-Office
New York, NY
145K-270K Annually
In-Office
New York, NY
145K-270K Annually

Similar Jobs

5 Days Ago
Hybrid
New York, NY, USA
Expert/Leader
Expert/Leader
Financial Services
As a Principal Software Engineer, you'll enhance and deliver technology products, provide architectural guidance, and lead cross-functional technical discussions, leveraging advanced skills in cloud technologies.
Top Skills: AWSCloud TechnologiesJavaNoSQLPythonSQLTerraform
13 Days Ago
Easy Apply
Hybrid
New York, NY, USA
Easy Apply
251K-340K Annually
Senior level
251K-340K Annually
Senior level
Healthtech • Pharmaceutical • Telehealth
Lead architectural decisions, mentor engineers, and drive technical strategies for scalable software systems, focusing on high-quality solutions and system health.
Top Skills: DatadogPython
13 Days Ago
Hybrid
New York, NY, USA
195K-292K Annually
Expert/Leader
195K-292K Annually
Expert/Leader
AdTech • Digital Media • Marketing Tech
The Principal Software Engineer oversees the architecture and deployment of data solutions, ensuring quality, efficiency, and compliance. They manage data integrity, guide technology collaboration, and lead the design and implementation of data systems and standards.
Top Skills: Artificial IntelligenceAws S3Big DataData PipelinesData StructuresDatabricksKubernetesMachine LearningMinioRedshiftTeradata

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech, a member of the Roche Group.

The Opportunity

At Prescient Design, we are building the Lab-in-the-Loop, Genentech’s AI for therapeutic molecular design platform. We are seeking an exceptional Principal Software Engineer to design and lead development for this product, and grow it into a platform that serves as the foundation for drug design within Roche. ( https://www.youtube.com/watch?v=cN1PxxQWoEc )

We are looking for someone with strong technical skills who is able to build reliable software and scale it. In addition, the ideal candidate has technical leadership experience, both in creating a roadmap and designing services, and in leading a small team of software engineers to execute the vision.

You will work closely with Prescient scientists and engineers, Genentech Computational Sciences (gCS) colleagues, Genentech Research & Early Development (gRED) Drug Discovery teams including the Antibody Engineering division, and other teams across the Roche family of companies to identify, strategize, and productionalize high-impact applications from across the drug discovery and development pipeline. Prescient Design provides a dynamic and challenging environment for cutting-edge, multidisciplinary research in AI and drug discovery including access to rich sources of data, close links to top academic institutions around the world, as well as internal Genentech and Roche partners and research units. 

In this role, you will:

  • Define and own the roadmap for the Prescient Lab-in-the-Loop platform, from product decisions to technical direction.

  • Build and maintain scalable and responsive web applications that integrate with our machine learning platform.

  • Work with Machine Learning Scientists and Engineers, and experimental specialists in large and small molecule design to build intuitive user interfaces, dashboards, and analytics tools.

  • Manage a small team of software engineers to execute in a fast-paced environment.

Who you are

  • 5 + years of software engineering work experience.

  • The ideal candidate will have industry experience working on AI services and infrastructure related topics

  • Proven track record of planning year long roadmaps in which shorter-term projects ladder to the long term-vision

  • 1+ years experience leading a team of software engineers

Preferred

  • Intense curiosity about the biology of disease and eagerness to contribute to scientific and computational efforts.

  • Proficiency with Python and SQL; familiarity with PyTorch preferred

  • Proficiency with at least one front-end framework such as React or angular

  • Experience in building and deploying scalable web applications

#gCS

#tech4lifeAI

Relocation benefits are available for this job posting

The expected salary range for this position based on the primary location of New York is $145,100 - 269,500 of hiring range.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

What you need to know about the NYC Tech Scene

As the undisputed financial capital of the world, New York City is an epicenter of startup funding activity. The city has a thriving fintech scene and is a major player in verticals ranging from AI to biotech, cybersecurity and digital media. It also has universities like NYU, Columbia and Cornell Tech attracting students and researchers from across the globe, providing the ecosystem with a constant influx of world-class talent. And its East Coast location and three international airports make it a perfect spot for European companies establishing a foothold in the United States.

Key Facts About NYC Tech

  • Number of Tech Workers: 549,200; 6% of overall workforce (2024 CompTIA survey)
  • Major Tech Employers: Capgemini, Bloomberg, IBM, Spotify
  • Key Industries: Artificial intelligence, Fintech
  • Funding Landscape: $25.5 billion in venture capital funding in 2024 (Pitchbook)
  • Notable Investors: Greycroft, Thrive Capital, Union Square Ventures, FirstMark Capital, Tiger Global Management, Tribeca Venture Partners, Insight Partners, Two Sigma Ventures
  • Research Centers and Universities: Columbia University, New York University, Fordham University, CUNY, AI Now Institute, Flatiron Institute, C.N. Yang Institute for Theoretical Physics, NASA Space Radiation Laboratory

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account