The role involves shaping commercial strategies for gene therapy programs, conducting market research, collaboration across departments, and supporting corporate strategy initiatives.
The Senior Manager, Corporate Strategy and New Product Planning will play a pivotal role in shaping the commercial direction of Lexeo’s leading cardiac programs and organization. With multiple catalysts expected in 2026, it is crucial to define and refine commercial assumptions as lead programs advance, and to support the expansion of Lexeo’s growing commercial organization and capabilities. This role focuses on characterizing the current and evolving landscape in gene therapy and rare cardiovascular disease, particularly Friedreich ataxia (FA) cardiomyopathy and arrhythmogenic cardiomyopathy (ACM). Additionally, this role will encompass corporate strategy responsibilities, supporting commercial development, pipeline strategy and prioritization and other high-impact projects with senior executives as Lexeo evolves.
Primary Responsibilities
- Conduct market research, including primary and secondary research, to outline market dynamics in FA, ACM and across other genetic medicine targets, such as unmet needs, key stakeholders, existing treatment paradigms, and competition, focusing on the U.S. and key international markets.
- Leverage research and insights to define how the company’s gene therapy candidates may meet unmet needs and impact future treatment paradigms.
- Collaborate closely with clinical colleagues to understand target product profiles and identify patient populations eligible for treatment.
- Identify and map key stakeholders involved in the treatment of FA and ACM, as well as those involved in the potential administration of cardiac gene therapy.
- Compile information on current treatment costs, payer perspectives, patient coverage types, treatment expenditure, and other medical costs.
- Analyze commercially available gene therapies in key markets, identifying successful constructs that maximize patient access or enable value-based reimbursement.
- Outline recommended investments and timelines for commercial scale-up over the next three years, including necessary commercial capabilities and colleagues.
- Develop and implement operational plans to ensure the efficient execution of commercial and corporate strategies.
- Support senior executives and business development colleagues with corporate strategy initiatives such as pipeline prioritization and development strategy optimization and other organizational planning
- Monitor and evaluate the performance of commercial initiatives, providing insights and recommendations for continuous improvement.
- Advance Lexeo objectives commercially, including support for corporate communications, media awareness, and internal employee initiatives that increase knowledge and understanding of lead programs and strategies
- Work closely with colleagues in Clinical Development, Medical Affairs, Program Management, and other relevant departments to ensure cohesive strategy execution.
- Report to the Senior Director of Commercial Marketing, regularly updating on project progress and strategic recommendations.
- Present findings and strategic recommendations to company leadership, facilitating informed decision-making.
Required Skills & Qualifications
- MBA with 7-10 years of professional experience in consulting, finance, marketing, sales, or biopharmaceuticals, with a focus on commercial strategy and operations.
- Experience in the healthcare and biopharmaceutical industry, with a deep understanding of global biopharmaceutical market trends.
- Proven ability to synthesize data from multiple sources and distill insights into clear, actionable business strategies.
- Strong project management skills with meticulous attention to detail and the ability to manage multiple priorities in a fast-paced environment.
- Excellent interpersonal communication skills and a track record of successful cross-functional collaboration.
- Ability to operate independently, driving projects to completion with minimal oversight.
About Lexeo
Lexeo Therapeutics is a clinical-stage genetic medicine company headquartered in New York City, pioneering cardiac genetic medicine candidates to treat the root causes of inherited cardiovascular diseases. Our lead program, LX2006, targets cardiomyopathy associated with Friedreich’s Ataxia and anchors a broader pipeline addressing genetically defined conditions such as hypertrophic and arrhythmogenic cardiomyopathies. Backed by a strong financial foundation, Lexeo is positioned to translate groundbreaking science into durable clinical impact.
Our work culture is a hybrid model with 2 days/week in the New York City office and 3 days working from home.
Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.
Top Skills
Commercial Strategy
Gene Therapy
Market Research
LEXEO Therapeutics New York, New York, USA Office
345 Park Avenue South, 6th Floor, New York, NY, United States, 10010
Similar Jobs
Fintech • News + Entertainment • Software • Database • Financial Services
The Accounts Receivable Specialist at Octus will monitor collections, manage client relationships, prepare invoices, and support audits.
Top Skills:
ExcelMS OfficeSage IntacctSalesforce
AdTech • Cloud • Digital Media • Information Technology • News + Entertainment • App development
Lead end-to-end product lifecycle for enterprise solutions (data warehouse/BI), own roadmaps and backlogs, gather stakeholder requirements, collaborate with engineering and architecture, perform data analysis to inform decisions, manage QA/UAT, incidents, vendor performance, and documentation to ensure compliant, high-quality product delivery.
Top Skills:
Jira,Agile,Sdlc,Data Warehouse,Business Intelligence Platforms
AdTech • Cloud • Digital Media • Information Technology • News + Entertainment • App development
Manage end-to-end product lifecycle for enterprise data and content platforms. Define vision, prioritize roadmaps, gather stakeholder requirements, collaborate with engineering and architecture, drive data-driven decisions, oversee QA/UAT, manage incidents and vendor performance, and maintain documentation and governance.
Top Skills:
Jira,Agile,Data Warehouse,Business Intelligence
What you need to know about the NYC Tech Scene
As the undisputed financial capital of the world, New York City is an epicenter of startup funding activity. The city has a thriving fintech scene and is a major player in verticals ranging from AI to biotech, cybersecurity and digital media. It also has universities like NYU, Columbia and Cornell Tech attracting students and researchers from across the globe, providing the ecosystem with a constant influx of world-class talent. And its East Coast location and three international airports make it a perfect spot for European companies establishing a foothold in the United States.
Key Facts About NYC Tech
- Number of Tech Workers: 549,200; 6% of overall workforce (2024 CompTIA survey)
- Major Tech Employers: Capgemini, Bloomberg, IBM, Spotify
- Key Industries: Artificial intelligence, Fintech
- Funding Landscape: $25.5 billion in venture capital funding in 2024 (Pitchbook)
- Notable Investors: Greycroft, Thrive Capital, Union Square Ventures, FirstMark Capital, Tiger Global Management, Tribeca Venture Partners, Insight Partners, Two Sigma Ventures
- Research Centers and Universities: Columbia University, New York University, Fordham University, CUNY, AI Now Institute, Flatiron Institute, C.N. Yang Institute for Theoretical Physics, NASA Space Radiation Laboratory


