Top Engineering Jobs in New York City, NY

Build and operate reliable cloud infrastructure, developer platforms, CI/CD systems, observability, and production workloads. Support applications, data systems, ML pipelines, and AI workloads across development, staging, and production. Establish SLOs, monitoring, incident response, automation, infrastructure-as-code practices, and operational standards. Collaborate with Product Engineering, Data Engineering, Data Science, and Security while mentoring engineers and participating in support rotations.

Build and operate backend-focused production software, APIs, integrations, databases, distributed systems, and asynchronous workflows. Develop AI-enabled and agentic systems with retrieval, tool use, evaluation, permissions, observability, and reliability controls. Own products from definition through iteration, collaborate with data engineering, data science, and SRE, make pragmatic technical tradeoffs, and mentor engineers.

Build and operate production software for active clinical trials, including clinical-system integrations, trial data flows, site activation, monitoring, and signal detection. Design AI-native agents and pipelines with auditability, provenance tracking, and human review in regulated GxP environments. Own multi-quarter technical initiatives, collaborate with clinical, regulatory, QA, data, and infrastructure teams, mentor engineers, and improve validated software delivery workflows.

Lead the infrastructure and SRE team, setting technical direction for reliable, secure, and scalable engineering systems. Hire, coach, and develop engineers; oversee multi-cloud infrastructure, Kubernetes, IaC, CI/CD, observability, incident response, support rotations, and regulated workloads. Partner across engineering, data science, security, and operations to improve developer experience and enable safe AI-assisted software delivery. Manage infrastructure roadmaps, budgets, resourcing, documentation, and organizational reliability practices.

Lead bioanalytical strategy and execution for drug development programs, manage CROs, oversee assay validation and data review for clinical trials.