Leads enterprise architecture for Pfizer’s patient services platforms, including data models, integrations, Salesforce ecosystems, governance, compliance, and AI-enabled patient and HCP experiences. Provides technical direction, architecture standards, impact assessments, and oversight for delivery teams. Partners with enterprise technology, security, legal, privacy, quality, and business teams to reduce technical debt and develop scalable capabilities supporting enrollment, benefits verification, prior authorization, assistance programs, specialty pharmacy, adherence, and case management.
Use Your Power for Purpose
The Director, Enterprise Architect is a technical leader within Pfizer's U.S. Patient Support Services (PSS) organization. Enterprise architect is accountable for developing and maintaining a scalable technology architecture, core platform data model and align with enterprise teams on integration approach to reduce overall technical and process debt. Enterprise architect will partner with business engagement team and delivery team to provide direction and approval for solution design, build estimation model and provide technical oversight to delivery teams.
What You Will Achieve
Enterprise Architecture and Standards
Integration and Data
Governance
Here Is What You Need (Minimum Requirements)
Bonus Points If You Have (Preferred Requirements)
Other Job Details
The annual base salary for this position ranges from $162,900.00 to $271,500.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Information & Business Tech
The Director, Enterprise Architect is a technical leader within Pfizer's U.S. Patient Support Services (PSS) organization. Enterprise architect is accountable for developing and maintaining a scalable technology architecture, core platform data model and align with enterprise teams on integration approach to reduce overall technical and process debt. Enterprise architect will partner with business engagement team and delivery team to provide direction and approval for solution design, build estimation model and provide technical oversight to delivery teams.
What You Will Achieve
Enterprise Architecture and Standards
- Own the technical architecture, data model and enterprise alignment for patient services process, including patient and HCP enrollment, benefits verification and re-verification, prior authorization and appeals support, copay and patient assistance programs, free goods and bridge programs, specialty pharmacy triage, adherence and education programs, and case management
- Produce and maintain current-state and target-state architecture, develop architecture guidelines and design principles for the development team.
- Own and maintain the business and technical data dictionary for patient services and partner with insights team ensure enterprise alignment on reporting.
- Use process mining and operational data to identify technology / AI process improvement opportunities to enhance business outcomes.
- Ensure right balance between enterprise capability and disease areas specific requirements, to ensure scalable platform capabilities.
Integration and Data
- Own and maintain integration patterns across Salesforce and patient services ecosystems, data platforms, Hub solutions and 3rd party integrations
- Ensure alignment with enterprise data platforms, integration patterns, Salesforce strategy
- Work closely with Enterprise salesforce team to build scalable capabilities for patient services field teams that can increase access of therapies to patients.
- Ensure architectures meet SOX, GxP, privacy, and security requirements
- Define patterns for observability, audibility, and controls in AI systems
- Partner with CISO, Legal, Privacy, and Quality to embed compliance by design
Governance
- Lead structured impact assessments for proposed process, platform, and vendor changes - covering downstream systems, data, integrations, reporting, controls, hub and vendor operations, field teams, and the patient experience
- Maintain traceability from Enterprise capability to process to system to control, so the blast radius of any change can be established quickly and evidenced
- Architect patient and HCP experiences on AI lead front technologies to reduce time to refill and enable field forces efficiencies.
- Set standards for grounding, prompt and agent versioning, conversation logging, evaluation, and audit evidence for AI in a regulated patient-facing context
- Govern org strategy, data model extension, declarative vs. programmatic build, technical debt, and release and environment management across the patient services
Here Is What You Need (Minimum Requirements)
- Applicant must have a bachelor's degree with at least 8 years of experience; OR a master's degree with at least 7 years of experience; OR a PhD with 5+ years of experience
- Required progressive experience in Enterprise architecture with focus on patient services Life Sciences domain
- Deep expertise in modern technology platforms including Salesforce, cloud ecosystems, DevOps, Agile methodologies, and AI.
- Very good understanding of commercialization process in bio-pharma domain
- Proven experience in change management, user adoption and process harmonization
- Strong program/project management and SDLC experience.
Bonus Points If You Have (Preferred Requirements)
- Deep expertise in enterprise architecture, solution design, and distributed systems
- Strong experience with CRM and commercial platforms (Salesforce, Veeva)
- Proven ability to design complex integrations and data architectures at scale
- Hands-on experience with cloud and data warehouse platforms (AWS, Azure, Snowflake, etc...) and modern data stacks
- Experience designing systems incorporating AI/ML and LLM-based capabilities
- Strong understanding of AI architectures (e.g. MCP)
- Expertise in security, compliance, and regulated environments (SOX, GxP)
- Ability to translate complex architecture into clear guidance for engineering teams
Other Job Details
- Last Date to Apply for Job: October 27, 2026
- Preferred Location: NYHQ / PA - Collegeville
- Ability to travel based on business needs
- NOT eligible for Relocation Package
- This position is hybrid and requires working from site, 2 to 3 days per week
The annual base salary for this position ranges from $162,900.00 to $271,500.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Information & Business Tech
Pfizer New York, New York, USA Office
Pfizer Hudson Yards Office



66 Hudson Blvd E, Suite 20, New York, NY, United States, 10001
Pfizer Madison, New Jersey, USA Office
1 Giralda Farms, Madison, NJ, United States, 07940
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