General Application — Research & Science

Welcome systems thinkers. System builds software to help the world see and solve anything as a system, starting in healthcare. We are a Public Benefit Corporation driven by purpose and shaped by values. We hire systems thinkers who are motivated by our purpose, share our values, and have the skills to advance our mission. 

At System, research is the origin of our most important ideas — and researchers work at the frontier of graph theory, clinical AI, causal inference, and knowledge representation to push the boundaries of what our platform can do.

• Develop and validate novel methods for modeling complex, interconnected systems
• Work at the intersection of graph theory, machine learning, and domain-specific knowledge
• Collaborate with Data Science and Engineering to transition research findings into production
• Publish and present findings that advance both the field and System's mission
• Partner with clinical and domain experts to ground research in real-world impact
• Contribute to a culture of intellectual rigor, curiosity, and continuous learning

• Master's or PhD in Computer Science, Statistics, Biomedical Informatics, or a related field
• A strong publication record or equivalent applied research experience
• Deep expertise in machine learning, statistical modeling, or computational methods
• Experience working with complex, heterogeneous, or graph-structured data
• Ability to communicate research findings clearly to both technical and non-technical audiences
• Comfort operating in a fast-paced startup environment alongside a long research horizon

• Experience with clinical NLP, EHR data, or healthcare ontologies (SNOMED, ICD, OMOP)
• Familiarity with knowledge graphs, semantic web technologies, or ontology engineering
• Background in causal inference, systems dynamics, or complex adaptive systems
• Experience collaborating with clinicians, policymakers, or public health researchers

• Think in systems — mapping feedback loops, interdependencies, and second-order effects comes naturally to you
• Are motivated by purpose-driven work, particularly at the intersection of technology and healthcare
• Believe technology should be a force for good and are drawn to the Public Benefit Corporation model
• Hold yourself and your work to a values-first standard, not just a deliverables-first one
• Lead with first principles and are comfortable questioning assumptions others take for granted
• See complexity as an invitation, not an obstacle — you thrive when problems are messy and interconnected
• Care about the downstream effects of what you build — on users, on systems, on society
• Operate with intellectual humility — always learning, always open to being wrong

Compensation:

Commensurate with experience and level. 

About System 

We aspire to help the world see itself differently and build a more responsible and values-driven model of a tech company. We are backed by top-tier VCs in Silicon Valley and New York and leading angel investors and founded by the former VP Data at Spotify. To learn more about what motivates our social mission, we invite you to read our blog here.

We believe in the power of autonomous, interdisciplinary, and diverse teams; in agile development; and in leading with values, first principles, and clear high-level priorities backed by data.  We believe in cultivating a growth mindset for our team — always learning, improving, being challenged, and having opportunities for professional and personal development.

System Inc. is an equal opportunity employer. We are proud to foster a workplace, in person and online, free from discrimination. We strongly believe that diversity of experience, perspectives, and backgrounds will lead to a better environment for our employees and a better product for our users. We are committed to providing access, equal opportunity and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. Job applicants must be legally authorized to work in the United States of America and must maintain ongoing work authorization during employment.