Operate the Commercial AI Council’s governance engine: manage use-case intake through disposition, own Tier 3 cases end-to-end, secure senior alignment, run biweekly Council meetings, maintain the AIR pipeline and playbook, partner with Digital/legal/compliance, track pipeline metrics, and implement process improvements to scale governance rigor and throughput.
Use Your Power for Purpose
The Senior Manager, Commercial AI Governance & Operations runs the operational engine of the Commercial AI Council, owning the use case lifecycle from intake through Council review and follow-through. This colleague is accountable for the quality of every use case that enters the pipeline, owns Tier 3 (Exploration) cases end to end, and secures senior leader alignment before elevating higher-tier use cases to the Senior Director for Council review. As the volume of submissions through the AI Innovation Registry (AIR) scales, this role sustains the speed, rigor, and credibility of how Commercial AI is governed.
What You Will Achieve:
Governance & decision-making
Council leadership
Pipeline & portfolio ownership
Standards, tools & continuous improvement
Here Is What You Need (Minimum Requirements)
Bonus Points If You Have (Preferred Requirements)
Work Location Assignment: Hybrid
The annual base salary for this position ranges from $124,400.00 to $207,400.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Mkt & Sales/Commercial Bus
The Senior Manager, Commercial AI Governance & Operations runs the operational engine of the Commercial AI Council, owning the use case lifecycle from intake through Council review and follow-through. This colleague is accountable for the quality of every use case that enters the pipeline, owns Tier 3 (Exploration) cases end to end, and secures senior leader alignment before elevating higher-tier use cases to the Senior Director for Council review. As the volume of submissions through the AI Innovation Registry (AIR) scales, this role sustains the speed, rigor, and credibility of how Commercial AI is governed.
What You Will Achieve:
Governance & decision-making
- Own quality control across all incoming use cases regardless of tier, accountable for the completeness, accuracy, and decision-readiness of every submission
- Own Tier 3 (Exploration) use cases end to end, from intake through evaluation and disposition, routing only the subset that require Council review
- Secure senior leader alignment ahead of Council review for all Council-bound cases (select Tier 3 (Exploration) and all Tier 2 (Incubation)), so they arrive decision-ready
- Elevate Tier 2 (Incubation) use cases to the Senior Director with a clear recommendation and routing path
- Apply and help evolve the governance standards, tier definitions, and evaluation criteria that determine how use cases move through the framework
- Develop and own communication standards across the governance process, including status updates to use case submitters and the format of Council recommendations
- Support legal and compliance discussions as needed
Council leadership
- Lead the biweekly Council operation end to end, owning the agenda, the decision-ready content, and the quality of what is put in front of senior leaders
- Partner with the Senior Director and Council members to frame decisions and ensure the right cases reach the table with clear, defensible recommendations
- Own the onboarding and integration of new functional areas (e.g., GAV) into the governance framework, from mapping through go-live
Pipeline & portfolio ownership
- Own the health of the AIR pipeline, accountable for throughput, cycle time, and quality across 20+ Tier 3 (Exploration) submissions per month
- Track and report pipeline status and decision velocity, surfacing risks and bottlenecks to leadership with recommended actions
Standards, tools & continuous improvement
- Own the Commercial AI Council Playbook, the AIR decision tree, and the governance documentation as the system of record, keeping them current with evolving standards
- Partner with Digital to maintain and enhance AIR, defining requirements and prioritizing system updates as governance needs evolve
- Identify and implement process improvements that scale the Council's capacity without compromising rigor
Here Is What You Need (Minimum Requirements)
- Applicant must have a bachelor's degree with at least 6 years of experience; OR a master's degree with at least 5 years of experience; OR a PhD with 1+ years of experience
- Experience in governance, program or portfolio management, or operations within the pharmaceutical or life sciences industry, including demonstrated end-to-end ownership of a process or program
- Experience running or facilitating cross-functional forums with senior leadership and converting input into decisions
- Sound, independent judgment with the ability to make and defend governance decisions
- Flexible and change-agile, able to expand scope and adapt ways of working as the Council's remit grows
Bonus Points If You Have (Preferred Requirements)
- Familiarity with AI and digital transformation initiatives and commercial operations
- Strong organizational skills with the ability to manage high-volume, fast-paced pipelines
- Detail-oriented with strong QC and documentation capabilities
Work Location Assignment: Hybrid
The annual base salary for this position ranges from $124,400.00 to $207,400.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Mkt & Sales/Commercial Bus
Pfizer New York, New York, USA Office
Pfizer Hudson Yards Office



66 Hudson Blvd E, Suite 20, New York, NY, United States, 10001
Pfizer Madison, New Jersey, USA Office
1 Giralda Farms, Madison, NJ, United States, 07940
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