Top Principal Data Scientist Jobs in NYC, NY

Develop and deploy advanced machine learning and data science solutions across large numeric and textual datasets. Partner with data scientists, engineers, and product managers to build customer-focused products. Lead model design, training, evaluation, validation, and implementation while researching emerging technologies and translating complex analyses into business outcomes.

Build and implement machine learning models for personal loan acquisition, including customer selection, campaign optimization, underwriting, pricing, and verification. Partner with data scientists, engineers, and product managers; analyze large-scale numeric and textual datasets using Python, Spark, AWS, and related tools; validate and backtest models; and translate statistical insights into customer-focused business outcomes.

Set the technical vision for data science, lead complex statistical and machine learning model development from concept through production, and architect scalable modeling platforms and pipelines. Develop credit risk, pricing, and loss forecasting models; establish model governance standards; partner with senior leaders; mentor data scientists; and communicate technical strategy to executives. The role emphasizes production deployment, monitoring, cloud architecture, and high-impact decision-making across the business.

Develops scalable self-service analytics, data science frameworks, predictive and causal models, experimentation strategies, semantic layers, and AI-powered analytics tools. Partners with Product, Engineering, Design, and data engineering teams to improve product adoption, engagement, retention, and monetization insights. Leads complex analytics initiatives, ensures analytical rigor and governance, communicates findings to executives, and mentors analysts and data scientists.

Lead research, design, and evaluation of large-scale detection models for automated, fraudulent, and malicious activity. Define measurement frameworks for noisy or incomplete ground truth, mentor data science practitioners, advance AI/ML techniques, and shape long-term detection strategy. Partner with ML Engineering, Data Engineering, and Product teams to influence roadmaps and protect Cloudflare customers from evolving threats.

Develop enterprise Generative AI solutions for Commercial Banking using multi-agent systems, advanced RAG, context engineering, and tool-calling frameworks. Partner with data scientists, machine learning engineers, and product managers to build, evaluate, validate, fine-tune, and deploy AI pipelines across numeric and textual data. Apply statistical modeling, machine learning, deep learning, NLP, information retrieval, and cloud technologies while translating complex technical work into business outcomes.

Lead end-to-end data science for customer-embedded, production solutions: acquire and prepare messy datasets, develop and evaluate models tied to business outcomes, run experiments, deploy operational models at scale, coach cross-disciplinary teams, and drive strategy, ethics, and privacy discussions.

Lead data science engagements with customers to acquire, clean, analyze, and model data; develop scalable operational models and evaluation methods; coach engineers on best practices; drive solution strategy, ethics, and industry thought leadership; write extensible code and collaborate across teams to deliver cloud-based AI solutions.

Leads the data science platform and machine learning strategy, building data marts, predictive models, MLOps infrastructure, and analytics capabilities. Analyzes healthcare claims, clinical, workflow, and operational data to risk-stratify patients, assess clinical program impact, support dashboards, and improve patient and provider engagement. Collaborates with clinical, operations, finance, product, executive, and technology teams while serving as a trusted analytics expert for a business workstream.

Lead end-to-end AI/ML initiatives to improve student retention, engagement, and enrollment. Architect and operate data pipelines, feature stores, and production ML systems; deploy, monitor, and automate models; run experimentation programing and measure business outcomes. Mentor team members and set technical standards across Product, Engineering, and CX.

Develop and deploy large-scale machine learning and personalization models for web and mobile customer experiences. Partner with data scientists, engineers, and product managers; analyze massive numeric and textual datasets; and manage model design, training, evaluation, validation, and implementation. Research advanced methods including foundation models, reinforcement learning, causal inference, transformer architectures, and recommender systems while translating technical findings into business outcomes.

Leads consumer personalization strategy and production development for recommendations, ranking, search, browse, carts, marketing, and agentic AI experiences. Builds recommender systems, learning-to-rank models, LLM agents, evaluation frameworks, and experimentation programs. Partners with Product and Engineering on deployment, monitoring, and model quality while mentoring senior data scientists, setting technical direction, shaping roadmaps, and communicating trade-offs to executives.

Lead the integration of advanced imaging analytics and AI in drug development, focusing on medical image analysis and clinical trials.

Lead data science projects to optimize drug development, develop AI models for clinical trials, and collaborate with teams on biomedical workflows.

Lead a team of data scientists to develop AI/ML solutions, leveraging advanced technologies for customer interactions and product innovations. Build and implement NLP models for large-scale applications while collaborating with cross-functional teams.

Lead G2’s experimentation practice across products and digital marketplaces. Design experimentation standards, causal inference methods, metrics, guardrails, and analysis approaches; partner with product and engineering to implement experimentation platforms and instrumentation. Build models, design auctions, ship production systems, evaluate modern statistical methods, and address marketplace interference and low-traffic constraints. Mentor data scientists and evangelize rigorous data science practices across the organization.

Leads the full machine learning lifecycle for foundational personalization and recommendation models, including client and item representations, embeddings, retrieval, ranking, and generative approaches. Designs experiments, evaluates business impact, deploys and operates production models, and works with large-scale behavioral, transactional, textual, and visual data. The role also involves technical leadership, cross-functional collaboration, mentoring, and establishing modeling and engineering best practices.

Lead development and deployment of machine learning models across the credit card lifecycle. Partner with cross-functional teams to build data-driven products, analyze large numeric and textual datasets, validate and implement models, and translate technical insights into business impact.

Lead development of next-generation entity resolution solutions using transformers, graph ML, deep learning, and big-data tooling. Partner with engineers and product to design, train, evaluate, validate, and deploy ML models at scale; leverage Agentic AI workflows; translate technical work into business impact across enterprise use cases.

Design, train, evaluate, and productionize machine learning models (including embeddings and foundation models) on large-scale data. Partner with product and engineering to run experiments, improve customer experiences, and deploy scalable solutions using Spark and AWS.

Staff and Principal Product Data Scientists will use advanced analytics, experimentation, causal inference, machine learning, and large-scale data technologies to guide Slack product strategy. They will define success metrics, build self-service reporting and data models, evaluate product adoption drivers, identify growth opportunities, and help develop Slack’s agentic data delivery platform. The role partners closely with Product, Design, Engineering, Product Research, and go-to-market teams while communicating insights to executives and cross-functional stakeholders.

Design, build, validate, and deploy machine learning models across the credit card lifecycle. Partner with cross-functional teams, analyze large numeric and textual datasets using Python, Spark, H2O and cloud platforms, and translate technical insights into business impact for card products.

Leads responsible AI and model governance while building and deploying healthcare fraud, waste, and abuse models. Establishes standards for documentation, monitoring, bias, drift, validation, and production readiness. Evaluates generative AI use cases, develops policies, validates large-scale claims models, and presents methodology and controls to partners, auditors, and investigators. Works remotely with data scientists, BI developers, and healthcare subject-matter experts.

Lead end-to-end data science initiatives for commercial property or homeowners insurance: acquire and prepare data, build and validate predictive models, deploy and monitor production models, ensure governance and documentation, advise teams, and evaluate emerging ML/AI techniques to improve pricing, risk selection, and underwriting outcomes.

The role involves collaborating with teams to develop AI-powered products, leveraging NLP and LLM technologies while operationalizing models into production systems.