Top Senior Machine Learning Engineer Jobs in NYC, NY

Design, implement, and maintain production-oriented NLP and LLM models; build data pipelines and HPC analyses; integrate ML solutions with clinical research tools; ensure data quality, privacy compliance, and collaborate across multidisciplinary teams.

Design, build, and support high-throughput, low-latency LLM inference and data pipelines; collaborate with data scientists to post-train and evaluate models; implement scalable, production-ready systems with strong testing, monitoring, and performance focus; mentor engineers and iterate on architecture, reliability, and user-facing AI applications.

Build and scale production machine learning systems for personalization and marketing optimization. Design end-to-end AI, reinforcement learning, recommendation, propensity, uplift, and lifetime-value pipelines; implement CI/CD, model versioning, monitoring, and orchestration; and lead agentic AI workflow automation. Collaborate with data science, engineering, marketing, and operations teams to productionize solutions. Provide technical leadership, mentor engineers and data scientists, and influence ML and data strategy.

The role involves leading the Observability Insights initiative at CoreWeave, focusing on developing APIs, agentic tools, and improving telemetry for AI systems. Candidates should possess significant experience in backend engineering and observability systems, especially for multi-tenant environments.

Develop and productize machine learning models for autonomous vehicle perception, including LiDAR and camera perception, sensor fusion, detection, classification, segmentation, and tracking. Build scalable data, training, metrics, and performance workflows, and implement efficient C++ code for the NVIDIA DRIVE AV platform. Collaborate across engineering teams, track advances in machine learning, and optimize models for real-time embedded inference.

Lead the design, development, deployment, and operation of machine learning models and platforms at scale. Build distributed ML infrastructure, data pipelines, cloud-based architectures, and production services. Develop and test application code, automate deployment, monitor and retrain models, and apply CI/CD, governance, security, and responsible AI practices. Collaborate with Product, Data Science, and Agile teams to solve complex business problems.

Build, train, evaluate, and deploy production machine learning and LLM systems for legal document intelligence. Develop NLP solutions for information extraction, summarization, search, AI agents, and document analysis. Create scalable ML pipelines, evaluation frameworks, and reliability metrics while optimizing model performance. Collaborate with engineering, product, legal, data, and security teams to deliver secure AI capabilities and translate business problems into production solutions.

Build and improve machine learning systems for ad ranking, relevance, personalization, and optimization. Responsibilities include feature pipelines, model training and evaluation, active learning, LLM-assisted labeling and synthetic data generation, experimentation, and low-latency production inference. The role partners with product, data, and platform teams to improve advertiser performance and user engagement while maintaining reliability, latency, and data quality.

Build and deploy scalable AI and machine learning products for clinical research, including patient recruitment, enrollment forecasting, and study feasibility. Develop ML models, LLM-powered agents, data pipelines, and MLOps infrastructure using cloud services and CI/CD automation. Collaborate with cross-functional teams to integrate AI into clinical research workflows, monitor model performance, and advance reliable, unbiased solutions that improve patient outcomes.

Supports payer modernization and health services consulting engagements by analyzing operational challenges, optimizing processes, applying business analytics, engaging stakeholders, implementing quality standards, and guiding transformation initiatives. Develops operational support frameworks, conducts market research, manages change, and advises clients on improving service delivery and business performance while mentoring junior team members.

Design and deploy production recommendation and retrieval engines, build data orchestration pipelines for multiple modalities, implement agentic workflow frameworks, and prototype, optimize, and scale models with monitoring, governance, and low-latency SLAs.

Own and improve Quora’s second-phase ranking models for feed and digest experiences. Build end-to-end machine learning systems covering data pipelines, candidate extraction, feature engineering, model training, and production integration. Identify new product applications for machine learning, develop efficient algorithms with other ML engineers, and contribute methodologies for large-scale recommendation systems.

Build and operate production machine learning systems for Safety AI, including low-latency APIs, data pipelines, model serving, evaluation, monitoring, and rollout infrastructure. Process large-scale camera and telematics data, optimize cloud and edge-to-cloud execution, track model performance and drift, and partner with applied scientists, firmware engineers, platform teams, and product managers to deliver reliable safety features.

Design, train, and deploy scalable ML models (generative, classification, regression). Define feature roadmaps, collaborate with engineering to implement code and APIs, adapt ML methods for distributed/GPU environments, and create evaluation/annotation programs for fine-tuning and performance measurement.

Develops and advances machine learning and deep learning models for personalized advertising recommendations. Responsibilities include understanding advertising systems and user behavior data, conducting foundational model research, validating approaches with large-scale compute, analyzing metrics, and collaborating with engineering and product teams to productionize research and deliver measurable business results.

Design, develop, and productionize machine learning and generative AI systems for document understanding, search, Q&A, virtual agents, and RAG applications. Build Python backend services, APIs, multi-agent architectures, retrieval infrastructure, and CI/CD pipelines. Manage the full ML lifecycle, evaluation, testing, telemetry, deployment, and troubleshooting while collaborating with cross-functional teams and maintaining healthcare data security and HIPAA compliance.

Design, develop, and productionize machine learning systems for document understanding, search, Q&A, GenAI, virtual agents, and RAG applications. Build Python backend services, AI APIs, multi-agent architectures, retrieval infrastructure, and CI/CD pipelines. Manage the full ML lifecycle, including training, validation, deployment, telemetry, A/B testing, and automated evaluation. Collaborate cross-functionally while ensuring scalable, secure, HIPAA-compliant healthcare solutions.

Build and operate production machine learning systems for Airbnb Payments, including LLM agents, real-time fraud detection, anomaly detection, personalization, and checkout optimization. Design, train, deploy, monitor, and continuously improve batch and streaming AI applications at global scale. Partner with product, engineering, operations, and data science teams, establish model governance and testing standards, and mentor engineers.

Architects, develops, and deploys high-performance machine learning systems across the full lifecycle. Responsibilities include large-scale feature engineering, online and offline pipelines, tree-based and deep learning models, low-latency serving, MLOps automation, model monitoring, and rigorous experimentation. The role requires production-grade software engineering, distributed computing, statistical expertise, and experience shipping ML systems in high-scale environments.

Lead end-to-end LLM inference performance across serving systems, models, GPU hardware, and workloads. Define rigorous benchmarks, diagnose bottlenecks from scheduling through kernels and interconnects, optimize single- and multi-node deployments, and deliver production-ready runtimes and configurations. Collaborate with product and infrastructure teams, evaluate inference technologies, and implement runtime fixes. The role requires strong Python engineering, production experience with serving engines such as vLLM or SGLang, GPU profiling, and knowledge of modern inference optimization techniques.

Own the machine learning and applied AI layer of a software platform, from research through production. Build text-processing pipelines, extract structured data from technical documents, develop LLM-powered decision workflows, create evaluation systems, and build NLP classifiers. Lead exploratory research, translate findings into product features, and collaborate with a small engineering team. The role is remote in the US or Canada, with quarterly travel.

Design, build, and deploy scalable AI and ML solutions by wrangling and integrating data, implementing models (Python/Java, TensorFlow, Scikit-Learn), developing data pipelines and NLP applications, collaborating with clients, and mentoring junior team members to drive business insights and regulatory risk solutions.

Lead exploration and application of large language models and generative AI for enterprise contact-center automation. Translate research into high-performing, deployable ML systems; contribute across experimentation, implementation, and deployment; collaborate with engineering and product teams; optimize performance; and help shape team strategy, innovation, and professional growth.

Lead exploration and application of large language models and generative AI, translate research into deployable ML systems, and guide strategic direction. Develop solutions across experimentation, implementation, and deployment while collaborating with engineering and product teams to optimize performance and customer outcomes in contact center automation.

Own the architecture and production delivery of a novel AI-powered exploitability engine. Lead probabilistic ranking, graph modeling, entity resolution, calibration, validation, and security guardrails for agentic systems. Drive zero-to-one technical direction, architecture, code reviews, cross-functional partnerships, and mentorship. Build scalable systems using distributed technologies, cloud-native development, APIs, databases, and machine learning while establishing defensible engineering decisions and evaluation metrics.