Top Senior Python Engineer Jobs in NYC, NY

Reposted 9 Days AgoSaved
Easy Apply
Remote or Hybrid
New York, NY
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
Senior level
Financial Services
Lead design and deliver production-grade trading systems using Python and Java, build AI-native platforms, champion AI-assisted engineering practices, partner with Credit Sales & Trading, support production stability, and drive adoption of secure, automated SDLC and cloud-native solutions.
Top Skills: Ai-Assisted Development ToolsAWSCi/CdJavaPython
Reposted 16 Hours AgoSaved
Remote or Hybrid
New York, NY
175K-215K Annually
Senior level
175K-215K Annually
Senior level
AdTech • Cloud • Digital Media • Information Technology • News + Entertainment • App development
Design and implement high-performance C++ systems for machine learning, computer vision, and 3D modeling. Apply research, optimize algorithms, manage source control with Git, deploy and test on cloud using Unix-based systems, and work with large-scale geospatial datasets to generate 3D content.
Top Skills: 3D ModelingBashC++Cloud PlatformCmakeComputer GraphicsComputer VisionDvcsGeospatial DataGitLinuxMachine LearningmacOSMercurialPythonUnix ShellUnreal Engine
Reposted 3 Days AgoSaved
In-Office
New York, NY
125K-350K Annually
Senior level
125K-350K Annually
Senior level
Information Technology • Software • Financial Services • Quantitative Trading
Design and develop software solutions, analyze complex problems, and provide support for trading activities in a dynamic environment.
Top Skills: C++KdbLinuxPythonSQL
Reposted 3 Days AgoSaved
Hybrid
New York, NY
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
The Senior Lead Data Engineer designs and develops technical solutions, leads a team of developers, and utilizes big data and cloud technologies to deliver robust solutions for Capital One.
Top Skills: AWSEmrGurobiHadoopHiveJavaKafkaLinuxMySQLNoSQLPythonRedshiftScalaSnowflakeSparkSQLUnix
Reposted 4 Days AgoSaved
Hybrid
New York, NY
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead diverse technology projects in distributed microservices and full stack systems, mentoring team members and collaborating with product managers on cloud-based solutions.
Top Skills: AWSCSSDockerGoGCPHTMLJavaJavaScriptKubernetesAzureNosql DatabasesOpen Source RdbmsPythonSQLTypescript
Reposted 4 Days AgoSaved
Remote or Hybrid
New York, NY
124K-280K Annually
Senior level
124K-280K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead the design and implementation of data architecture strategies within AI and ML, collaborating with stakeholders to enhance data solutions and ensure compliance with governance policies.
Top Skills: AWSAzureDatabricksFastapiGCPPythonSnowflakeSQL
Reposted 5 Days AgoSaved
Hybrid
New York, NY
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a team to develop distributed systems using Golang and Python on Kubernetes, collaborate on AI/ML solutions, and drive technological innovation.
Top Skills: AWSAzureCSSDockerGCPGoHTMLJavaJavaScriptKubernetesNoSQLPythonRdbmsSQLTypescript
Reposted 8 Days AgoSaved
Hybrid
New York, NY
209K-286K Annually
Senior level
209K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead full‑stack teams to design and deliver cloud-based, microservices solutions. Mentor engineers, collaborate with product managers, and build scalable systems using Python, ReactJS, AWS, containers, and modern data tools to meet regulatory and customer needs.
Top Skills: AWSDatabricksDockerGoGCPHTML/CSSJavaJavaScriptKubernetesAzureNoSQLPythonReactSnowflakeSQLTypescript
Reposted 4 Days AgoSaved
Hybrid
New York, NY
180K-220K Annually
Senior level
180K-220K Annually
Senior level
Artificial Intelligence • Healthtech • Insurance • Machine Learning • Payments
Alaffia Health seeks a Senior Python Engineer to develop AI-driven medical billing applications, focusing on backend API development and data processing. Responsibilities include collaborating across teams, improving observability practices, and ensuring successful project delivery.
Top Skills: AIAirflowAWSAws SqsAzureDagsterDatadogGCPKafkaKinesisMachine LearningPythonRelational Databases
Reposted 2 Days AgoSaved
Remote or Hybrid
New York, NY
144K-190K Annually
Senior level
144K-190K Annually
Senior level
Edtech • Information Technology • Software
Lead ownership of Pluralsight's Search backend: build and maintain scalable, reliable ingestion and query systems, design and analyze experiments, consume and produce platform data, collaborate cross-functionally, and participate in on-call rotation to resolve alerts and improve the system.
Top Skills: AlgoliaElasticsearchKafkaNode.jsPostgresPythonTypescript
Reposted 10 Days AgoSaved
In-Office
New York, NY
121K-182K Annually
Senior level
121K-182K Annually
Senior level
Fintech • Financial Services
Design and deliver scalable Python applications for mortgage trading, analytics, workflows, and reporting. Integrate platforms with business, risk, and product teams. Lead full development lifecycle, apply AI/GenAI to automate workflows and analysis, ensure CI/CD, testing, and production readiness, resolve complex issues, coach junior staff, and act as SME with limited supervision.
Top Skills: AICi/CdDockerGenaiKubernetesOpenshiftPython
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Reposted YesterdaySaved
In-Office or Remote
New York, NY
Senior level
Senior level
Agency • Information Technology
Design, build, test, and maintain backend applications using FastAPI and SQLAlchemy. Implement database schemas, integrate front-end components, optimize for performance and scalability, debug issues, participate in code reviews, and collaborate on feature design. Maintain clean, testable code and stay current with best practices.
Top Skills: FastapiGitMySQLOraclePytestPythonSQLSqlalchemy
Reposted 4 Days AgoSaved
Remote
New York, NY
200K-225K Annually
Senior level
200K-225K Annually
Senior level
Artificial Intelligence • eCommerce • Software
Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.
Top Skills: APIsAWSAzureDockerGCPKubernetesLlmsMachine LearningNoSQLPythonSQL
Reposted 4 Days AgoSaved
Remote
New York, NY
119K-206K Annually
Senior level
119K-206K Annually
Senior level
eCommerce • Retail
The role involves developing scalable backend services using Python, optimizing performance, integrating AI features, and collaborating with cross-functional teams.
Top Skills: AsyncioCi/CdContainerized DeploymentFastapiPythonRest Apis
Reposted 19 Days AgoSaved
Hybrid
New York, NY
209K-286K Annually
Senior level
209K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a portfolio of technology projects with a team of developers to create solutions for regulatory needs, collaborating on cloud-based projects while mentoring engineers.
Top Skills: Amazon SagemakerAWSCSSDatabricksDockerGoHTMLJavaJavaScriptKubernetesLuaMcpPythonSQLTypescript
Reposted 24 Days AgoSaved
Remote or Hybrid
New York, NY
77K-202K Annually
Mid level
77K-202K Annually
Mid level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
As a Senior Associate, the role involves designing data architecture, collaborating with stakeholders, and mentoring team members while ensuring data quality and implementing solutions using programming languages and cloud platforms.
Top Skills: DockerJavaPythonScalaSQL
Reposted YesterdaySaved
In-Office or Remote
New York, NY
40K-140K Annually
Senior level
40K-140K Annually
Senior level
Agency • Information Technology
Design and implement data federation and lakehouse architectures, build scalable ETL/ELT pipelines with Python and Spark, optimize performance across federated queries, manage Delta/Iceberg/Hudi tables, and enforce governance, security, and access controls for analytics and AI teams.
Top Skills: AdlsApache IcebergSparkAws EmrAzure DatabricksData FederationData LakehouseDbtDelta LakeDremioGCPGlueHudiKubernetesPulumiPysparkPythonS3SQLStarburstTerraformTrino (Presto)
Reposted 4 Days AgoSaved
In-Office
New York, NY
142K-213K Annually
Senior level
142K-213K Annually
Senior level
Fintech • Financial Services
Lead design, development, and maintenance of enterprise-grade Generative AI platforms and services using Python, Node.js, and TypeScript. Architect scalable AI integrations, work with data science and business stakeholders, deploy GenAI products, enforce coding and testing standards, mentor engineers, and ensure governance, risk, and operational best practices across Citi's GenAI ecosystem.
Top Skills: AiopsAPIsCi/CdExpressFastapiFlaskGenerative AiHugging FaceMicroservicesNestjsNode.jsPandasPublic CloudPythonScikit-LearnTypescript
8 Days AgoSaved
In-Office or Remote
New York, NY
160K-190K Annually
Senior level
160K-190K Annually
Senior level
eCommerce • Fintech • Payments • Software
Lead end-to-end automation projects that replace manual ops workflows with production-grade AI-driven, agentic orchestration. Partner with non-technical stakeholders to discover problems, architect and ship full-stack solutions, measure business impact, and maintain robust guardrails and error handling for reliable production use.
Top Skills: Ai AgentsCi/CdGitGithub ActionsJavaScriptLlmsPythonTypescript
Reposted 21 Days AgoSaved
Remote
New York, NY
Senior level
Senior level
Healthtech • Software
Lead backend development on the scheduling platform modernization, contribute across products, write APIs, and drive AI-accelerated software development workflows.
Top Skills: .NetAgent OrchestrationAi-Assisted DevelopmentLlm ToolingPython
9 Days AgoSaved
In-Office
New York, NY
Senior level
Senior level
Professional Services • Industrial • Manufacturing
Senior developer responsible for design and development of multi-tier applications using Java, C++ and Python. Must have strong object-oriented skills, standalone development experience, domain knowledge in derivatives/fixed income and regulatory reforms (Dodd-Frank), and strong communication with business and testing teams.
Top Skills: C++JavaMulti-Tier ApplicationsObject Oriented ProgrammingPython
Reposted YesterdaySaved
Remote or Hybrid
New York, NY
Senior level
Senior level
Digital Media • Social Media • Software • Design
Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.
Top Skills: Python
Reposted YesterdaySaved
In-Office or Remote
New York, NY
36K-126K Annually
Senior level
36K-126K Annually
Senior level
Agency • Information Technology
Design, develop, and maintain Airflow DAGs and ETL/ELT pipelines; integrate with databases, APIs, and cloud storage; optimize and monitor pipelines; troubleshoot failures; collaborate with data teams; ensure code quality, testing, deployment practices; document work and mentor junior engineers.
Top Skills: Apache AirflowAWSAzureDockerGCPKubernetesMySQLPostgresPythonSQL
Reposted YesterdaySaved
Remote
New York, NY
38K-133K Annually
Senior level
38K-133K Annually
Senior level
Agency • Information Technology
Design, build, test, and maintain high-performance Python data applications and backend services. Lead technical design, review code, mentor junior engineers, integrate with databases and cloud services, optimize performance, and ensure security, scalability, and reliability.
Top Skills: DjangoFastapiFlaskGitLinux/UnixMicroservicesMongoDBMySQLNoSQLPostgresPythonRestful ApisSQL
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