Top Senior Python Engineer Jobs in NYC, NY

Reposted 8 Days AgoSaved
Hybrid
New York, NY
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead diverse technology projects in distributed microservices and full stack systems, mentoring team members and collaborating with product managers on cloud-based solutions.
Top Skills: AWSCSSDockerGoGCPHTMLJavaJavaScriptKubernetesAzureNosql DatabasesOpen Source RdbmsPythonSQLTypescript
Reposted 9 Days AgoSaved
Hybrid
New York, NY
209K-286K Annually
Senior level
209K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a portfolio of technology projects with a team of developers to create solutions for regulatory needs, collaborating on cloud-based projects while mentoring engineers.
Top Skills: Amazon SagemakerAWSCSSDatabricksDockerGoHTMLJavaJavaScriptKubernetesLuaMcpPythonSQLTypescript
Reposted 10 Days AgoSaved
In-Office
New York, NY
125K-350K Annually
Senior level
125K-350K Annually
Senior level
Information Technology • Software • Financial Services • Quantitative Trading
Design and develop software solutions, analyze complex problems, and provide support for trading activities in a dynamic environment.
Top Skills: C++KdbLinuxPythonSQL
Reposted 25 Days AgoSaved
Easy Apply
Remote or Hybrid
New York, NY
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
Reposted 13 Days AgoSaved
Remote or Hybrid
New York, NY
77K-202K Annually
Mid level
77K-202K Annually
Mid level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
As a Senior Associate, the role involves designing data architecture, collaborating with stakeholders, and mentoring team members while ensuring data quality and implementing solutions using programming languages and cloud platforms.
Top Skills: DockerJavaPythonScalaSQL
Reposted 2 Days AgoSaved
Remote
New York, NY
Senior level
Senior level
Information Technology
The Senior Python Developer will design and implement secure backend systems using Python and Pyodide, ensuring compliance with DoD cybersecurity requirements and cloud deployment practices. Responsibilities include leading Python code optimization, supporting CI/CD pipelines, and participating in Agile sprint cycles, all while collaborating with cross-functional teams and ensuring secure coding standards.
Top Skills: 800-171APIsCi/CdCloud OneCmmcDevsecopsDisa StigsNist Sp 800-53PyodidePythonWebassemblyZero Trust
13 Days AgoSaved
Hybrid
New York, NY
180K-220K Annually
Senior level
180K-220K Annually
Senior level
Artificial Intelligence • Healthtech • Insurance • Machine Learning • Payments
Alaffia Health seeks a Senior Python Engineer to develop AI-driven medical billing applications, focusing on backend API development and data processing. Responsibilities include collaborating across teams, improving observability practices, and ensuring successful project delivery.
Top Skills: AIAirflowAWSAws SqsAzureDagsterDatadogGCPKafkaKinesisMachine LearningPythonRelational Databases
Reposted 18 Days AgoSaved
Hybrid
New York, NY
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
The Senior Lead Data Engineer designs and develops technical solutions, leads a team of developers, and utilizes big data and cloud technologies to deliver robust solutions for Capital One.
Top Skills: AWSEmrGurobiHadoopHiveJavaKafkaLinuxMySQLNoSQLPythonRedshiftScalaSnowflakeSparkSQLUnix
19 Days AgoSaved
Remote or Hybrid
New York, NY
124K-280K Annually
Senior level
124K-280K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead the design and implementation of data architecture strategies within AI and ML, collaborating with stakeholders to enhance data solutions and ensure compliance with governance policies.
Top Skills: AWSAzureDatabricksFastapiGCPPythonSnowflakeSQL
20 Days AgoSaved
Hybrid
New York, NY
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead a team to develop distributed systems using Golang and Python on Kubernetes, collaborate on AI/ML solutions, and drive technological innovation.
Top Skills: AWSAzureCSSDockerGCPGoHTMLJavaJavaScriptKubernetesNoSQLPythonRdbmsSQLTypescript
Reposted 22 Days AgoSaved
Hybrid
New York, NY
230K-286K Annually
Senior level
230K-286K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
The Senior Lead Software Engineer will lead diverse tech projects, mentor developers, and deliver cloud-based solutions using various programming languages and technologies.
Top Skills: AWSDockerGoGCPJavaKubernetesAzureNode.jsPythonScalaSQL
Reposted 17 Days AgoSaved
In-Office
New York, NY
121K-181K Annually
Senior level
121K-181K Annually
Senior level
Fintech • Financial Services
The role involves developing complex reporting solutions, automating report needs, and transforming data infrastructure in collaboration with various stakeholders.
Top Skills: ClojureETLKdbNoSQLOraclePythonQlikviewSQL ServerSsrsTableau
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Reposted 9 Days AgoSaved
Remote
New York, NY
119K-206K Annually
Senior level
119K-206K Annually
Senior level
eCommerce • Retail
The role involves developing scalable backend services using Python, optimizing performance, integrating AI features, and collaborating with cross-functional teams.
Top Skills: AsyncioCi/CdContainerized DeploymentFastapiPythonRest Apis
12 Days AgoSaved
Remote
New York, NY
Senior level
Senior level
Healthtech • Software
Lead backend development on the scheduling platform modernization, contribute across products, write APIs, and drive AI-accelerated software development workflows.
Top Skills: .NetAgent OrchestrationAi-Assisted DevelopmentLlm ToolingPython
Reposted 3 Days AgoSaved
In-Office or Remote
New York, NY
175K-250K Annually
Senior level
175K-250K Annually
Senior level
AdTech • Marketing Tech • Social Impact • Software • Analytics
The Senior AI/ML Engineer will develop and improve analytical tools, approaches, and architecture for scalable AI and machine learning solutions, collaborating with engineers and data scientists on innovative projects.
Top Skills: CeleryFlaskGraphQLJavaScriptMongoDBNode.jsNumpyPandasPythonScikit-LearnScipyVue
Reposted 4 Days AgoSaved
In-Office
New York, NY
Senior level
Senior level
Information Technology • Software
The role involves design and development of multi-tier applications using Java and C++, requiring knowledge of Python and derivatives domain.
Top Skills: C++JavaPython
Reposted 4 Days AgoSaved
In-Office
New York, NY
Senior level
Senior level
Information Technology • Software
The role requires a senior developer with expertise in Java and C++, and knowledge of Python. Responsibilities include designing and developing multi-tier applications and handling regulatory projects.
Top Skills: C++JavaPython
5 Days AgoSaved
In-Office
New York, NY
177K-265K Annually
Senior level
177K-265K Annually
Senior level
Fintech • Financial Services
Lead design and hands-on delivery of scalable, high-performance Python applications for market and regulatory risk. Architect distributed systems, implement CI/CD, secure REST APIs, collaborate with quants and DevOps, and drive Stress Testing and Regulatory Risk projects under tight deadlines.
Top Skills: Agentic Ai ToolsAngularSparkAWSAzureBitbucket PipelinesCassandraClaudeDevinDjangoDockerFastapiFlaskGCPGitGithub ActionsGithub CopilotGitlab CiGoogle GeminiHadoopJenkinsKafkaKubernetesMongoDBOpenai GptOracleOwasp Top 10PostgresPytestPython 3.XPyTorchReactRedisRestful ApisScikit-LearnSQLSQL ServerTensorFlowUnittestUnixVue
Reposted 18 Days AgoSaved
Remote
New York, NY
200K-225K Annually
Senior level
200K-225K Annually
Senior level
Artificial Intelligence • eCommerce • Software
Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.
Top Skills: APIsAWSAzureDockerGCPKubernetesLlmsMachine LearningNoSQLPythonSQL
7 Days AgoSaved
In-Office
New York, NY
120K-228K Annually
Senior level
120K-228K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, implement, and scale event-driven, distributed backend systems in Python on AWS to process and enrich large-scale document and media datasets. Lead technical projects, mentor engineers, integrate ML/LLM components, optimize performance, maintain observability, and collaborate with Data Science, ML Engineering, and Product to deliver reliable high-throughput content processing services.
Top Skills: AirflowAWSCloudwatchDatabricksDatadogEcsElasticacheLambdaLlmMachine LearningPythonScalaSnsSparkSqsTerraform
7 Days AgoSaved
In-Office
New York, NY
120K-228K Annually
Senior level
120K-228K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, build, and scale event-driven, distributed backend systems in Python to extract and enrich metadata at massive scale. Lead architecture, mentor engineers, integrate ML/LLM components, optimize performance, and ensure observability and reliability across AWS-based pipelines.
Top Skills: AirflowAws CloudwatchAws EcsAws ElasticacheAws LambdaAws SnsAws SqsDatabricksDatadogLlmMachine LearningPythonScalaSparkTerraform
20 Days AgoSaved
Remote
New York, NY
90-110 Annually
Senior level
90-110 Annually
Senior level
Digital Media • Professional Services • Consulting • Financial Services
The Senior Python Developer will enhance commerce and communication infrastructure by developing features, collaborating with stakeholders, ensuring system reliability, and integrating with third-party tools, while maintaining high-performance standards.
Top Skills: Ci/CdDockerFastapiPostgresPythonRabbitMQRedisStripe
8 Days AgoSaved
In-Office or Remote
New York, NY
160K-190K Annually
Senior level
160K-190K Annually
Senior level
eCommerce • Fintech • Payments • Software
Design and build end-to-end AI-driven automation to replace manual operational workflows. Partner with ops, sales, and support to discover problems, architect agentic orchestration, deploy production systems, measure impact, and iterate with robust guardrails and error handling.
Top Skills: Ai AgentsApexAutogenAWSAzureCi/CdClaude CodeCrewaiCursorGCPGitGithub ActionsGithub CopilotJavaScriptJIRALanggraphLightningLlmsPythonSalesforceSalesforce ApisSlackTypescriptWindsurf
Reposted 10 Days AgoSaved
In-Office or Remote
New York, NY
Senior level
Senior level
Software
The Senior Full-Stack Engineer will develop and maintain scalable web applications using Python and React, design APIs, and deploy applications on AWS.
Top Skills: AWSDjangoDockerFastapiFlaskGithub ActionsGitlab Ci/CdGoogle Maps ApiJenkinsLeafletMapboxMongoDBMySQLPostgisPostgresPythonReactStripe
Reposted YesterdaySaved
New York, NY
Senior level
Senior level
AdTech • Fintech • Information Technology • Database
Design and implement high-performance system software for medical devices, collaborating with hardware engineers and ensuring adherence to clinical standards.
Top Skills: C++Python
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