Top Senior Python Engineer Jobs in NYC, NY

Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.

Founding engineer responsible for architecting and building core product components, writing scalable Python code, designing and maintaining AI/ML infrastructure, implementing testing and CI/CD best practices, shipping backend production systems, collaborating on product roadmap, and mentoring future engineers.

Design, build, and maintain scalable data pipelines and tenant-aware APIs to ingest and transform data from varied sources. Work with event-driven and batch architectures, implement authentication and integration patterns, ensure observability/monitoring, optimize data flows for cost and performance, and collaborate with product, infrastructure, and engineering teams to onboard and maintain data sources at scale.

Founding engineer responsible for architecting and building core product systems, writing scalable Python backend code, designing and maintaining AI/ML infrastructure, instituting best development practices (testing, CI/CD), collaborating on product roadmap, and mentoring future engineers.

Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.

Lead Software Engineer responsible for designing, developing, testing, and maintaining a distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements, implement cloud and big-data solutions (Spark/Hadoop), and ensure program standards and reliable delivery.

Lead development of Python-based web applications using Django and FastAPI, architect scalable solutions, and establish technical standards while mentoring developers and optimizing infrastructure.

The Senior Software Engineer will develop features, maintain quality, review code, and collaborate on product design for the EnrollWise platform, focusing on back-end and some front-end work.

Develop and enhance features for EnrollWise, contribute to a scalable software architecture, review code, collaborate on design and technical feasibility, and maintain software quality.

Lead backend development on the scheduling platform modernization. Contribute across Python and .NET ecosystems, write APIs, review code, and support AI-accelerated development workflows while collaborating in a remote team environment.

Lead design, development, and maintenance of enterprise-grade Generative AI platforms and services using Python, Node.js, and TypeScript. Architect scalable AI integrations, work with data science and business stakeholders, deploy GenAI products, enforce coding and testing standards, mentor engineers, and ensure governance, risk, and operational best practices across Citi's GenAI ecosystem.

Lead the design and development of scalable Python backend services and APIs on AWS, mentor engineers, and manage PostgreSQL databases in a healthcare technology environment.

Build and maintain full-stack wealth management platform features using Python and Angular or React. Design service-oriented architectures and REST/SOAP APIs, work with relational databases and ORMs, contribute to AWS or Azure cloud architecture, and deploy using container technologies. Collaborate in Agile/Scrum ceremonies, participate in code reviews and demos, and work independently with distributed teams.

Design and build modern GCP lakehouse architectures, including Python and Spark pipelines, BigQuery ingestion, Kafka CDC, Delta Lake and Iceberg UniForm integrations, Delta Sharing endpoints, Snowflake and Databricks connectivity, data lineage, governed access controls, and semantic-layer alignment. Collaborate cross-functionally, troubleshoot full-stack issues, and deliver reusable data-sharing adapters and end-to-end data features.

Lead design, build, and operate scalable backend services and carrier integrations. Provide technical leadership, mentor engineers, drive architecture and best practices, write and test code, troubleshoot production incidents, and improve monitoring and reliability while collaborating with product and cross-functional teams.

Design and build full-stack applications that expose AI/ML insights. Develop backend services in Python, RESTful APIs, and containerized microservices. Build high-performance front-end interfaces with React/Vue/Angular. Implement cloud-native solutions on Google Cloud or Azure, manage relational and NoSQL databases, apply testing and CI/CD, and participate in Agile development and architecture sessions.

Design, build, and scale Python backend services and agentic LLM workflows for a multi-tenant, regulated enterprise platform. Productionize LLM integrations (Bedrock), ensure security/compliance, implement async orchestration, optimize data layers (Postgres, vector search/RAG), and add observability, real-time eventing, and typed API contracts. Collaborate cross-functionally and drive architecture to production.

Senior developer responsible for design and development of multi-tier applications using Java, C++ and Python. Must have strong object-oriented skills, standalone development experience, domain knowledge in derivatives/fixed income and regulatory reforms (Dodd-Frank), and strong communication with business and testing teams.

Design, develop, and maintain features for Gradio and Trackio, architect Python frameworks, collaborate with contributors, and enhance user experience for ML web apps.

Design, build, and own a multi-tenant enterprise SaaS backend that feeds ML data and BI. Collaborate with product, data science, UX, and users to deliver scalable, reliable customer-facing AI solutions. Drive systems design, database schemas, development lifecycle standards, technical docs, and code reviews while using AI/agentic tools to accelerate development.

Design, develop, and maintain Airflow DAGs and ETL/ELT pipelines; integrate with databases, APIs, and cloud storage; optimize and monitor pipelines; troubleshoot failures; collaborate with data teams; ensure code quality, testing, deployment practices; document work and mentor junior engineers.

Design, build, test, and maintain high-performance Python data applications and backend services. Lead technical design, review code, mentor junior engineers, integrate with databases and cloud services, optimize performance, and ensure security, scalability, and reliability.

Build and maintain full-stack production applications and services that integrate frontier LLMs. Design, test, and stress-test systems, diagnose failures, prototype rapidly, and collaborate with engineering and research teams to deliver reliable, deployable software and evaluation tooling.

Design and implement scalable backend and distributed systems for a marketing intelligence platform. Build near-real-time ingestion and processing, scale an incrementality/experimentation product, integrate AI-powered workflows, improve data ingestion/exports and connection-state systems, and contribute frontend components to deliver end-to-end product experiences.

Senior backend engineer on an education-focused technology consulting team. Own complex backend systems end-to-end: estimate scope, build and support production Python services, design REST/GraphQL APIs, work with cloud and Docker, use relational databases, maintain strong automated tests and Git workflows, and represent technical work to clients. Role values mentorship, ownership, and mission-driven work.