Top Chief of Staff Jobs in NYC, NY

Act as the founders' right hand to operationalize AI: prototype internal AI workflows, turn experiments into company-wide programs, run executive cadence and OKRs, unblock cross-functional projects, prepare strategic briefs, enforce responsible AI guardrails, and drive exit-readiness and organizational health.

Run marketing org operations and planning cadence, translate VP priorities into executable plans, manage budget/headcount trade-offs, ensure cross-functional coordination, own leadership materials and special projects, and improve org cadence and accountability so programs ship on time and leaders focus on strategy.

Serve as a strategic partner to the CEO and leadership team, driving cross-functional, high-priority initiatives end-to-end (strategy, go-to-market, product, operations). Strengthen operational infrastructure, support sales and client-facing materials, analyze data, build models and KPIs, and ensure execution and follow-through on critical projects.

The Chief of Staff drives operational effectiveness, supports leadership priorities, manages cross-functional projects, and ensures effective communication within the company.

The Director will extend the CEO's capacity by managing various strategic and operational priorities, working across functions, and transforming ambiguous tasks into actionable plans.

As Chief of Staff to the CRO, you'll drive commercial strategy, lead cross-functional projects, negotiate complex partnerships, and improve revenue operations while building a team.

Serve as Chief of Staff to Product & Technology leadership and lead the P&T PMO: establish program frameworks and tooling, drive cross-functional programs (notably H2 2026 hiring), manage planning cycles (headcount, OKRs, budgets), remove organizational blockers, and support CEO/CTO/CPO on strategic initiatives and board prep.

The role involves developing strategic partnerships, collaborating with leadership on planning, and managing project budgets to support health system growth.

Support leadership by executing high-impact, ad-hoc and non-scalable tasks. Manage cross-functional projects, solve operational problems, and enable strategic initiatives through hands-on execution.

Serve as the founders' connective tissue: draft and send executive communications, oversee day-to-day operations, manage end-to-end hiring, track action items and deliverables, act as founders' proxy in operational contexts, and build processes and systems to scale company operations.

As Chief of Staff, partner with the CEO to lead strategic initiatives, ensure alignment across the organization, and manage key business processes in a dynamic environment.

Work directly with the Co-CEO to translate strategy into execution: create action plans, track top-priority initiatives, surface customer insights, remove operational bottlenecks, and drive cross-functional execution across GTM, Product, Research, Engineering and Finance. Own critical initiatives, maintain executive-level visibility, and develop deep functional and technical understanding of products and roadmap.

The Chief of Staff will work closely with the CEO and CTO, coordinating projects, managing communications, arranging events, overseeing operational finance, and leading strategic initiatives in a high-growth startup environment.

Serve as a strategic operator and trusted liaison to the CEO, managing the Office of the CEO, executive schedule, internal communications, information flow, and cross-functional coordination. Track CEO OKRs, facilitate leadership meetings, draft and review external/internal briefing materials, staff the CEO at events, and lead high-level projects while acting as a proxy for the CEO when needed.

Serve as the primary operator for a portfolio of elite physicians: manage relationships, run opportunity pipeline, drive deal execution, shape physician positioning and content, maintain contracts/invoices/workflows, and build repeatable playbooks to scale a tech-enabled physician talent platform.

Serve as the CEO's operational counterpart owning day-to-day operations, special projects, strategic planning, finance/HR operations, multi-state program rollouts, and building repeatable playbooks to scale the company across legal, product, operations, and GTM functions.

The Chief of Staff will facilitate strategy execution, improve operational frameworks, and enhance cross-functional alignment within the Data organization at Coursera.

Senior-level program manager and chief of staff supporting the CVP of Operations. Own and drive high-priority cross-functional programs from kickoff through execution, establish operating cadences, align teams on priorities, prepare leadership materials, integrate sales & operations, headcount and infrastructure planning, surface risks, and remove execution blockers to ensure organizational KPIs and milestones are met.

Operate as the President's right hand to launch 0-to-1 strategic projects, manage high-stakes external partnerships and donors, and run the organization's operating rhythm. Lead validation experiments, drive cross-functional execution across HR/legal/finance, represent Schoolhouse to partners, and improve core workflows like hiring and retreats to advance the 2028 vision.

Work directly with the CEO and CFO to translate executive priorities into execution: lead strategic initiatives, run executive operating rhythms (meetings, OKRs), synthesize decision-ready materials, coordinate cross-functional workstreams, support finance with analysis and board/investor materials, and represent leadership in confidential matters.

The Chief of Staff will support the CEO and leadership team, manage stakeholder relationships, build content and communicate data-driven insights, and drive organization within the team. They will also lead special projects and help in recruiting and team culture initiatives.

Serve as strategic partner to the President & CEO, oversee programmatic operations across youth development, reentry, wellness, and workforce initiatives; supervise program leaders; ensure compliance with funder requirements; coordinate cross-functional projects, performance management, and community partnerships to advance organizational priorities and program outcomes.

The Chief of Staff will support the CEO by driving strategy, managing cross-functional initiatives, and enhancing organizational alignment to achieve economic transformation goals.

The Chief of Staff / Integrator will manage operations for two eCommerce brands, driving execution, improving workflows, and building operational systems to support growth.

Own the company's operating cadence, accelerate decision-making, lead high-priority cross-functional projects, and manage OKRs to ensure strategic accountability and scalable operations.