Top Senior Python Jobs in NYC, NY

Design and develop software solutions, analyze complex problems, and provide support for trading activities in a dynamic environment.

Designs and develops APIs, system integrations, and AI-agent workflows for enterprise applications. Builds integrations with platforms such as Salesforce and REST APIs, deploys and supports solutions on AWS, and develops AI-powered automation using LLMs, tool calling, and multi-step workflows. The role includes client requirements gathering, troubleshooting, reliability optimization, cross-functional collaboration, and mentoring junior developers.

Designs, develops, deploys, and operates scalable Go and Python microservices in distributed production environments. Responsibilities include API design, Kubernetes deployment, monitoring, scaling, troubleshooting incidents, system architecture, security, testing, code reviews, and continuous improvements to development processes and infrastructure. The role requires end-to-end service ownership, strong Linux and Docker expertise, observability knowledge, and experience with reliability, performance, and CI/CD practices.

Lead backend-focused software architecture and development across distributed systems, data ingestion, experimentation platforms, AI workflows, and product capabilities. Build primarily in Python while contributing to React and TypeScript frontend work. Translate ambiguous product needs into scalable production systems, guide technical direction, partner with product and data teams, mentor engineers, and improve engineering practices.

Develop and maintain open-source Python frameworks and ML developer tools, architect scalable libraries, grow early-stage projects, build real-time streaming capabilities, integrate modern frontend technologies, and collaborate with open-source contributors and the broader developer community.

Design and maintain scalable Python backend services, enterprise data integration frameworks, batch pipelines, REST APIs, and AWS cloud-native applications. Build serverless solutions using Lambda, DynamoDB, API Gateway, EventBridge, SQS, and Step Functions. Improve data pipeline observability, resilience, monitoring, and performance while supporting analytics, machine learning, and AI use cases. Collaborate with stakeholders and engineering teams, troubleshoot distributed systems, mentor junior engineers, conduct code reviews, and promote modern development and DevOps practices.

Build and maintain scalable backend applications, serverless functions, microservices, data workflows, ETL pipelines, and cloud-native architectures using Python and AWS. Manage databases, APIs, batch jobs, and real-time integrations while optimizing performance, scalability, security, compliance, and cost. Collaborate with product, engineering, analytics, and data teams; contribute to architecture, CI/CD, infrastructure automation, development standards, and technical mentorship. Healthcare claims data experience is required.

The Senior Full-Stack Engineer will develop and maintain scalable web applications using Python and React, design APIs, and deploy applications on AWS.

As a Senior Python Developer, you'll build financial systems, develop microservices, and utilize cloud-native technologies on AWS, while ensuring code quality and performance.

Develop open source SDKs, enterprise APIs, UIs, and backend systems supporting large-scale computer vision datasets. Build scalable, maintainable, performant, and well-tested software for unstructured data and AI workflows. Contribute to enterprise deployments across customer clouds and on-premises environments, while improving tooling, automation, engineering practices, and open source community initiatives in a remote-first team.

The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.

The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.

Develop Python-based solutions performing SQL/CRUD database operations, extract/transform/generate files (CSV, XML, JSON, PDF), and implement email integrations. Work within an onsite/offshore model, communicate clearly, and perform reliably under high-pressure conditions.

Develop and maintain high-scale, high-performance, highly available server systems using Python and frameworks (Django/Flask). Build REST/SOAP/JSON APIs, integrate message buses (RabbitMQ/ActiveMQ, Kafka preferred), and work with Cassandra and distributed system tools like Zookeeper. Apply algorithms, distributed systems knowledge, and Agile/Scrum practices.

The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.

Develop and enhance features for EnrollWise, contribute to a scalable software architecture, review code, collaborate on design and technical feasibility, and maintain software quality.

Build and maintain full-stack wealth management platform features using Python and Angular or React. Design service-oriented architectures and REST/SOAP APIs, work with relational databases and ORMs, contribute to AWS or Azure cloud architecture, and deploy using container technologies. Collaborate in Agile/Scrum ceremonies, participate in code reviews and demos, and work independently with distributed teams.

Develop and maintain front, middle, or back-office trading platforms for investment banks. Work on trade capture, real-time multithreaded risk portals, and rewrite reporting with precognitive error checking and auto-correct features. Collaborate across teams and explain technical solutions to non-technical stakeholders.

Senior developer responsible for design and development of multi-tier applications using Java, C++ and Python. Must have strong object-oriented skills, standalone development experience, domain knowledge in derivatives/fixed income and regulatory reforms (Dodd-Frank), and strong communication with business and testing teams.

Design and implement scalable backend and distributed systems for a marketing intelligence platform. Build near-real-time ingestion and processing, scale an incrementality/experimentation product, integrate AI-powered workflows, improve data ingestion/exports and connection-state systems, and contribute frontend components to deliver end-to-end product experiences.

The role requires a senior developer with expertise in Java and C++, and knowledge of Python. Responsibilities include designing and developing multi-tier applications and handling regulatory projects.

The role involves design and development of multi-tier applications using Java and C++, requiring knowledge of Python and derivatives domain.

The role involves backend development using SQL, mentoring junior staff, participating in project delivery, and ensuring robust team processes.

Contract Python Developer to build backend services using Django/Flask. Requires strong object-oriented Python, familiarity with C++ STL, and front-end skills (HTML, CSS, JavaScript, jQuery or Angular). 6+ month contract based in Brooklyn, NY.

Develop and maintain backend services using Python (strong OOP) with Django or Flask; some C++ STL work. Build/integrate front-end components using HTML, CSS, JavaScript and jQuery or Angular. Contract role based in NYC.